경희대학교 한의과대학 배현수 교수 연구실
Prof. Hyunsu Bae / College of Korean Medicine, Kyung Hee Univeristy, Seoul, Korea
of 전체검색 결과
- 게시판
- 4개
- 게시물
- 155개
3/16 페이지 열람 중
기타논문 게시판 내 결과
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Screening of phytochemicals effective on relieving cancer cachexia in cisplatin‑induced in vitro sarcopenia model
새창
Abstract Background Cancer cachexia is a lethal metabolic syndrome induced by cancer and chemotherapy administration and characterized by marked muscle wasting. Although hormone-related cancer therapies have been used for treatment of the cachexia, they have several side effects…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 15:21:37 -
TAMpepK Suppresses Metastasis through the Elimination of M2-Like Tumor-Associated Macrophages in Triple-Negative Breast Cancer
새창
Abstract: Triple-negative breast cancer (TNBC) accounts for approximately 10–15% of all breast cancer cases and is characterized by high invasiveness, high metastatic potential, relapse proneness, and poor prognosis. M2-like tumor-associated macrophages (TAMs) contribute to tumorigenesis and are pro…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 15:18:46 -
The Responsiveness of Bee Venom Phospholipase A2 on Regulatory T Cells Correlates with the CD11c+CD206+Population in Human Peripheral Blood Mononuclear Cells
새창
Abstract: Bee venom phospholipase A2 (bvPLA2) has been reported to have therapeutic effects such as neuroprotection, anti-inflammation, anti-nociception, anti-cancer properties, caused by increasing regulatory T cells (Tregs). The mechanism of Tregs modulation by bvPLA2 has been …
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 13:53:48 -
Subcutaneous toxicity of melittin‑dKLA in ICR mice
새창
Abstract Background Melittin, a major component of honeybee venom, is known to possess anti-allergic, anti-inflammatory, antiarthritis, and anti-cancer. Despite its great promise as an agent for various diseases, the therapeutic applications of melittin have been severely limite…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 13:48:47 -
Targeting of adipose tissue macrophages by bee venom phospholipase A2 attenuates high-fat diet-induced obesity
새창
Abstract Background/objectives Adipose tissue macrophages (ATMs) exist in either the M1 or M2 form. The anti-inflammatory M2 ATMs accumulate in lean individuals, whereas the pro-inflammatory M1 ATMs accumulate in obese individuals. Bee venom phospholipase A2 (bvPLA2), a major co…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 13:41:51 -
Evaluation of the Efficacy and Safety of the Herbal Formula PM014 in a Cisplatin- and Paclitaxel-Treated Tumor-Bearing Mouse Model
새창
AbstractPM014 (HL301) is a standardized herbal mixture derived from a traditional Korean medicine, Chung-Sang-Bo-Ha-Tang. Previously, we reported that PM014 treatment significantly suppressed pulmonary fibrosis, one of the frequent adverse effects of anticancer therapy in lung cancer. Before the cli…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2020-10-29 15:19:57 -
Inhibitory effects of bee venom on mast cell-mediated allergic inflammatory responses
새창
Abstract Although bee venom (BV) is a toxin that causes bee stings to be painful, it has been widely used clinically for the treatment of certain immune‑associated diseases. BV has been used traditionally for the treatment of chronic inflammatory diseases. In this regard, the present study analyzed…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2019-07-26 15:25:28 -
Comparison of the Protective Effects of Bee Venom Extracts with Varying PLA2 Compositions in a Mouse Model of Parkinson’s Disease
새창
AbstractBee venom contains a number of pharmacologically active components, including enzymes and polypeptides such as phospholipase A2 (PLA2) and melittin, which have been shown to exhibit therapeutic benefits, mainly via attenuation of inflammation, neurotoxicity, and nociception. The …
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2019-07-26 15:19:21 -
Prophylactic Effects of Bee Venom Phospholipase A2 in Lipopolysaccharide-Induced Pregnancy Loss
새창
AbstractSpontaneous abortion represents a common form of embryonic loss caused by early pregnancy failure. In the present study, we investigated the prophylactic effects of bee venom phospholipase A2 (bvPLA2), a regulatory T cell (Treg) inducer, on a lipopolysaccharide (LPS)-induced abortion mouse…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2019-07-26 15:00:28 -
Comparison of Administration Routes on the Protective Effects of Bee Venom Phospholipase A2 in a Mouse Model of Parkinson’s Disease
새창
Parkinson’s disease (PD) is the second most common neurodegenerative disorder worldwide. Progressive loss of dopaminergic neurons in the substantia nigra (SN) and their synaptic terminal connections in the striatum are main characterizations of PD. Although many efforts have been made to develop the…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2018-11-16 15:21:01