경희대학교 한의과대학 배현수 교수 연구실
Prof. Hyunsu Bae / College of Korean Medicine, Kyung Hee Univeristy, Seoul, Korea
effect 전체검색 결과
- 게시판
- 1개
- 게시물
- 66개
1/7 페이지 열람 중
기타논문 게시판 내 결과
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Enhanced Therapeutic Effect of Optimized Melittin-dKLA, a Peptide Agent Targeting M2-like Tumor-Associated Macrophages in Triple-Negative Breast Cancer
새창
DOI https://doi.org/10.3390/ijms232415751 JOURNAL International Journal of Molecular Sciences TITLE Enhanced Therapeutic Effect of Optimized Melittin-dKLA, a Peptide Agent Targeting M2-like Tumor-As…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-12-16 14:32:59 -
Therapeutic Effect of Melittin–dKLA Targeting Tumor-Associated Macrophages in Melanoma
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Abstract: Melanoma is an immunogenic tumor and a serious type of skin cancer. Tumor-associated macrophages (TAMs) express an M2-like phenotype and are involved in all stages of melanomagenesis; it is hence a promising target for cancer immunotherapy. We herein investigated whethe…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-15 10:14:59 -
Screening of phytochemicals effective on relieving cancer cachexia in cisplatin‑induced in vitro sarcopenia model
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Abstract Background Cancer cachexia is a lethal metabolic syndrome induced by cancer and chemotherapy administration and characterized by marked muscle wasting. Although hormone-related cancer therapies have been used for treatment of the cachexia, they have several side effects…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 15:21:37 -
Inhibitory effects of bee venom on mast cell-mediated allergic inflammatory responses
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Abstract Although bee venom (BV) is a toxin that causes bee stings to be painful, it has been widely used clinically for the treatment of certain immune‑associated diseases. BV has been used traditionally for the treatment of chronic inflammatory diseases. In this regard, the present study analyzed…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2019-07-26 15:25:28 -
Comparison of the Protective Effects of Bee Venom Extracts with Varying PLA2 Compositions in a Mouse Model of Parkinson’s Disease
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AbstractBee venom contains a number of pharmacologically active components, including enzymes and polypeptides such as phospholipase A2 (PLA2) and melittin, which have been shown to exhibit therapeutic benefits, mainly via attenuation of inflammation, neurotoxicity, and nociception. The …
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2019-07-26 15:19:21 -
Prophylactic Effects of Bee Venom Phospholipase A2 in Lipopolysaccharide-Induced Pregnancy Loss
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AbstractSpontaneous abortion represents a common form of embryonic loss caused by early pregnancy failure. In the present study, we investigated the prophylactic effects of bee venom phospholipase A2 (bvPLA2), a regulatory T cell (Treg) inducer, on a lipopolysaccharide (LPS)-induced abortion mouse…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2019-07-26 15:00:28 -
Comparison of Administration Routes on the Protective Effects of Bee Venom Phospholipase A2 in a Mouse Model of Parkinson’s Disease
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Parkinson’s disease (PD) is the second most common neurodegenerative disorder worldwide. Progressive loss of dopaminergic neurons in the substantia nigra (SN) and their synaptic terminal connections in the striatum are main characterizations of PD. Although many efforts have been made to develop the…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2018-11-16 15:21:01 -
Protective Effects of Intratracheally-Administered Bee Venom Phospholipase A2 on Ovalbumin-Induced Allergic Asthma in Mice
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Abstract: Asthma is a common chronic disease characterized by bronchial inflammation, reversible airway obstruction, and airway hyperresponsiveness (AHR). Current therapeutic options for the management of asthma include inhaled corticosteroids and 2 agonists, which elicit harmful side effects. In t…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2016-09-22 20:02:01 -
Neuro-protective effects of Ligustri Fructus by suppression of oxidative stress in mouse model of Parkinson’s disease
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Abstract Parkinson’s disease (PD) is a progressive degenerative disorder of the central nervous system (CNS) that leads to impairment of motor skills and speech. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) causes damage to the dopaminergic (DA) neurons, and 1-4-Methyl-4-phenylpyridinium (MP…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2016-07-12 14:47:08 -
Immunotherapy with methyl gallate, an inhibitor of Treg cell migration, enhances the anti-cancer effect of cisplatin therapy
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Abstract Foxp3+ CD25+CD4+ regulatory T (Treg) cells are crucial for the maintenance of immunological self-tolerance and are abundant in tumors. Most of these cells are chemo-attracted to tumor tissues and suppress anti-tumor responses inside the tumor. Currently, several cancer immunoth…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2016-07-12 14:43:11