경희대학교 한의과대학 배현수 교수 연구실
Prof. Hyunsu Bae / College of Korean Medicine, Kyung Hee Univeristy, Seoul, Korea
cr 전체검색 결과
- 게시판
- 4개
- 게시물
- 51개
2/6 페이지 열람 중
기타논문 게시판 내 결과
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Therapeutic Effect of Melittin–dKLA Targeting Tumor-Associated Macrophages in Melanoma
새창
Abstract: Melanoma is an immunogenic tumor and a serious type of skin cancer. Tumor-associated macrophages (TAMs) express an M2-like phenotype and are involved in all stages of melanomagenesis; it is hence a promising target for cancer immunotherapy. We herein investigated whethe…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-15 10:14:59 -
Screening of phytochemicals effective on relieving cancer cachexia in cisplatin‑induced in vitro sarcopenia model
새창
Abstract Background Cancer cachexia is a lethal metabolic syndrome induced by cancer and chemotherapy administration and characterized by marked muscle wasting. Although hormone-related cancer therapies have been used for treatment of the cachexia, they have several side effects…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 15:21:37 -
TAMpepK Suppresses Metastasis through the Elimination of M2-Like Tumor-Associated Macrophages in Triple-Negative Breast Cancer
새창
Abstract: Triple-negative breast cancer (TNBC) accounts for approximately 10–15% of all breast cancer cases and is characterized by high invasiveness, high metastatic potential, relapse proneness, and poor prognosis. M2-like tumor-associated macrophages (TAMs) contribute to tumorigenesis and are pro…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 15:18:46 -
Subcutaneous toxicity of melittin‑dKLA in ICR mice
새창
Abstract Background Melittin, a major component of honeybee venom, is known to possess anti-allergic, anti-inflammatory, antiarthritis, and anti-cancer. Despite its great promise as an agent for various diseases, the therapeutic applications of melittin have been severely limite…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 13:48:47 -
Targeting of adipose tissue macrophages by bee venom phospholipase A2 attenuates high-fat diet-induced obesity
새창
Abstract Background/objectives Adipose tissue macrophages (ATMs) exist in either the M1 or M2 form. The anti-inflammatory M2 ATMs accumulate in lean individuals, whereas the pro-inflammatory M1 ATMs accumulate in obese individuals. Bee venom phospholipase A2 (bvPLA2), a major co…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 13:41:51 -
Magnoliae Cortex Alleviates Muscle Wasting by Modulating M2 Macrophages in a Cisplatin-Induced Sarcopenia Mouse Model
새창
Abstract: Cachexia causes high mortality, low quality of life, and rapid weight loss in cancer patients. Sarcopenia, a condition characterized by the loss of muscle, is generally present in cachexia and is associated with inflammation. M2 macrophages, also known as an anti-inflam…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 13:31:43 -
Macrophage Depletion Protects against Cigarette Smoke-Induced Inflammatory Response in the Mouse Colon and Lung
새창
Cigarette smoke (CS) is considered as a major risk factor for pulmonary and intestinal inflammation. CS leads to macrophage infiltration in the mucosae of the lung and colon, inducing the uncontrolled secretion of inflammatory mediators, and thus promoting inflammatory response. In this study, we in…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2018-11-16 15:15:04 -
Screening of acetylcholinesterase inhibitors in herbal medicines
새창
Abstract The pathogenesis of Alzheimer’s disease (AD) has been linked to a deficiency in the brain neurotransmitter acetylcholine. Subsequently, acetylcholinesterase (AChE) inhibitors were used for the treatment of mild to moderate AD. The goal of this study was determine the candidate therapeutic…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2015-08-27 14:49:10 -
Screening for herbal medicines that affect ZIC1 gene methylation in colorectal cancer
새창
Abstract The zinc finger of the cerebellum (ZIC1) is a tumor suppressor gene that is silenced through promoter hypermethylation in colorectal cancer. This study was conducted to evaluate the efficacy of herbal medicines to demethylate the ZIC1 gene in colorectal cancer. We evaluated the effects of …
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-17 00:21:08 -
A novel synthetic compound 4-Acetyl-3-methyl-6-(2-bromophenyl)pyrano[3,4-c] pyran-1,8-dione inhibits the production of nitric oxide and proinflammatory cytokines Via the NF-κB pathway in lipopolysaccharide-activated microglia cells
새창
Abstract Previously, we discovered a new compound, 1H,8H-Pyrano[3,4-c]pyran-1,8- dione (PPY), from Vitex rotundifolia L. and evaluated its anti-inflammatory and anti-asthmatic effects. In this study, we synthesized a new, modified compound 4-acetyl-3-methyl-6-(2-bromophenyl)pyrano[3,4-c]pyran-1,8-d…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-17 00:08:17