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5/15 페이지 열람 중
기타논문 게시판 내 결과
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Expression levels of the hypothalamic AMPK gene determines the responsiveness of the rats to electroacupuncture-induced analgesia
새창
Abstract Background: Although electroacupuncture (EA) relieves various types of pain, individual differences in the sensitivity to EA analgesia have been reported, causing experimental and clinical difficulties. Our functional genomic study using cDNA microarray identified that 5'-AMP-activate…
최고관리자 2014-12-17 01:15:09 -
Treatment with pyranopyran-1, 8-dione attenuates airway responses in cockroach allergen sensitized asthma in mice
새창
Abstract Chronic allergic asthma is characterized by Th2-typed inflammation, and contributes to airway remodeling and the deterioration of lung function. Viticis Fructus (VF) has long been used in China and Korea as a traditional herbal remedy for treating various inflammatory diseases. Previously,…
최고관리자 2014-12-17 01:13:32 -
Metergoline inhibits the neuronal Nav1.2 voltage-dependent Na+ channels expressed in Xenopus oocytes
새창
Abstract Aim:Metergoline is an ergot-derived psychoactive drug that acts as a ligand for serotonin and dopamine receptors. The aim of this study was to investigate the regulatory effects of metergoline on the neuronal Nav1.2 voltage-dependent Na+ channels in vitro.Methods:Xenopus oocytes were injec…
최고관리자 2014-12-17 01:11:26 -
Gyejigachulbu-Tang relieves oxaliplatin-induced neuropathic cold and mechanical hypersensitivity in rats via the suppression of spinal glial activation
새창
Abstract Activation of spinal glial cells plays a crucial role in the pathogenesis of neuropathic pain. An administration of oxaliplatin, an important anticancer drug, often induces acute neuropathic cold hypersensitivity and/or mechanical hypersensitivity in patients. Gyejigachulbu-tang (GBT), a h…
최고관리자 2014-12-17 01:04:56 -
The effects of maekmoondong-tang on cockroach extract-induced allergic asthma
새창
Abstract Maekmoondong-tang (MMDT) has long been used in Asian countries to treat respiratory diseases. However, the precise mechanisms underlying its effects on asthma are unknown. This study was conducted to evaluate the protective effects of MMDT in a cockroach allergen (CKA-)induced animal model…
최고관리자 2014-12-17 01:02:35 -
Effect of achyranthes bidentata blume on 3T3-L1 adipogenesis and rats fed with a high-fat diet
새창
Abstract The present study investigated the antiobesity effect of Achyranthes bidentata Blume root water extract in a 3T3-L1 adipocyte differentiation model and rats fed with a high-fat diet. To investigate the effect of Achyranthes bidentata Blume on adipogenesis in vitro, differentiating 3T3-L1 c…
최고관리자 2014-12-17 00:47:15 -
Electroacupuncture analgesia is improved by adenoviral gene transfer of dopamine beta-hydroxylase into the hypothalamus of rats
새창
Abstract Electroacupuncture (EA) is a modified form of acupuncture that utilizes electrical stimulation. We previously showed that EA stimulated rats were divided into responders that were sensitive to EA and non-responders that were insensitive to EA based on the tail flick latency (TFL) test. The…
최고관리자 2014-12-17 00:44:06 -
A synthetic compound, 4-acetyl-3-methyl-6-(3,4,5-trimethoxyphenyl)pyrano[3, 4-c]pyran-1,8-dione, ameliorates ovalbumin-induced asthma
새창
Abstract Eosinophilia is one of the characteristic signs of allergic inflammation. Massive migration of eosinophils to the airways can cause epithelial tissue injury, contraction of airway smooth muscle and increased bronchial responsiveness. Previously, we discovered a new compound, 1H,8H-pyrano[3…
최고관리자 2014-12-17 00:32:55 -
Paeonol, a major compound of Moutan Cortex, attenuates cisplatin-induced nephrotoxicity in mice
새창
Abstract Cisplatin is an effective chemotherapeutic agent that is used for the treatment of a variety of cancers; however, its nephrotoxicity limits the use of this drug. In the present study, we examined whether paeonol, a major compound of Moutan Cortex, has protective effects on cisplatin-induce…
최고관리자 2014-12-17 00:28:32 -
Screening for herbal medicines that affect ZIC1 gene methylation in colorectal cancer
새창
Abstract The zinc finger of the cerebellum (ZIC1) is a tumor suppressor gene that is silenced through promoter hypermethylation in colorectal cancer. This study was conducted to evaluate the efficacy of herbal medicines to demethylate the ZIC1 gene in colorectal cancer. We evaluated the effects of …
최고관리자 2014-12-17 00:21:08