The 전체검색 결과
- 게시판
- 4개
- 게시물
- 101개
5/11 페이지 열람 중
기타논문 게시판 내 결과
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The standardized herbal formula, PM014, ameliorated cigarette smoke-induced lung inflammation in a murine model of chronic obstructive pulmonary disease
새창
Abstract Background: In this study, we evaluated the anti-inflammatory effect of PM014 on cigarette smoke induced lung disease in the murine animal model of chronic obstructive pulmonary disease (COPD).Methods: Mice were exposed to cigarette smoke (CS) for 2 weeks to induce COPD-like lung inflammat…
최고관리자 2014-12-17 00:17:52 -
The effects of Gamijinhae-tang on elastase/lipopolysaccharide-induced lung inflammation in an animal model of acute lung injury
새창
Abstract Background: Gamijinhae-tang (GJHT) has long been used in Korea to treat respiratory diseases. The therapeutic effect of GJHT is likely associated with its anti-inflammatory activity. However, the precise mechanisms underlying its effects are unknown. This study was conducted to evaluate th…
최고관리자 2014-12-17 00:14:07 -
The neuroprotective effect of gugijihwang-tang on trimethyltin-induced memory dysfunction in the rat
새창
Abstract Gugijihwang-Tang (the herbal formula PM012), a decoction consisting of several herbs including Rehmanniae Radix Preparata, has been widely used as herbal treatment for dementia. In order to investigate the neuroprotective action of this prescription, we examined the effect of Gugijihwang-T…
최고관리자 2014-12-17 00:10:45 -
A novel synthetic compound 4-Acetyl-3-methyl-6-(2-bromophenyl)pyrano[3,4-c] pyran-1,8-dione inhibits the production of nitric oxide and proinflammatory cytokines Via the NF-κB pathway in lipopolysaccharide-activated microglia cells
새창
Abstract Previously, we discovered a new compound, 1H,8H-Pyrano[3,4-c]pyran-1,8- dione (PPY), from Vitex rotundifolia L. and evaluated its anti-inflammatory and anti-asthmatic effects. In this study, we synthesized a new, modified compound 4-acetyl-3-methyl-6-(2-bromophenyl)pyrano[3,4-c]pyran-1,8-d…
최고관리자 2014-12-17 00:08:17 -
Prophylactic effects of Lonicera japonica extract on dextran sulphate sodium-induced colitis in a mouse model by the inhibition of the Th1/Th17 response
새창
Abstract Inflammatory bowel diseases (IBD) are chronically relapsing inflammatory disorders of the intestine. Although some therapeutic agents, including steroids, are available for the treatment of IBD, these agents have limited use. Therefore, dietary supplements have emerged as possible interven…
최고관리자 2014-12-17 00:02:18 -
Screening herbal medicines for the recovery of alpha-synuclein-induced Parkinson's disease model of yeast
새창
Abstract The goal of this study was quantitatively determine the recovery effects of herbal medicines (HM) on the alpha-synuclein (α-Syn)-induced Parkinson's disease. In the present study, the detoxification effects of 270 HM in a yeast model of Parkinson's disease that had been damaged b…
최고관리자 2014-12-16 23:58:47 -
Phenelzine (monoamine oxidase inhibitor) increases production of nitric oxide and proinflammatory cytokines via the NF-κB pathway in lipopolysaccharide-activated microglia cells
새창
Abstract Phenelzine is a potent monoamine oxidase inhibitor that is used in patients with depression. It is also well known that nitric oxide (NO) synthase inhibitors show preclinical antidepressant-like properties, which suggests that NO is involved in the pathogenesis of depression. The purpose o…
최고관리자 2014-12-16 23:55:05 -
The effects of Foxp3 on gene expression profiles in activated microglial cells
새창
Abstract Microglia constitutes the first line of defense against infection and injury in the brain. We previously demonstrated that activated microglia express the Foxp3 gene. However, the role of Foxp3 in cells other than Treg is generally unknown. Therefore, this study was conducted to determine …
최고관리자 2014-12-16 23:40:52 -
Microarray analysis of the gene expression profile of HMC-1 mast cells following Schizonepeta tenuifolia Briquet treatment
새창
Abstract It has long been believed that mast cells play a crucial role in the development of many physiological changes during immediate allergic responses. This study was conducted to evaluate the anti-inflammation mechanism of. Schizonepeta tenuifolia (ST) extract and ST purified chemicals on the…
최고관리자 2014-12-16 21:52:07 -
The comparative analysis of in vivo and in vitro transcriptome data based on systems biology
새창
Abstract We investigated whether an in vitro cellbased system can represent toxicity of an in vivo organ using gene expression profiles. We performed an analysis of differentially expressed transcripts, pathway analysis, and Gene Ontology (GO) grouping with the toxicity-induced data following treat…
최고관리자 2014-12-16 21:42:06