경희대학교 한의과대학 배현수 교수 홈페이지

기타논문 게시판 내 결과

• Anti-inflammatory effects of Scutellaria baicalensis water extract on LPS-activated RAW 264.7 macrophages 새창

  Abstract Aim of the study: The root of Scutellaria baicalensis Georgi (Labiatae), also known as Scutellariae Radix, possesses anticancer, antiviral, and anti-inflammatory properties. And it is one of the most widespread herbal remedies used in Oriental medicine. In the present study, we investigate…

  최고관리자 2014-12-16 19:12:33
• Inhibition effects of Vitex rotundifolia on inflammatory gene expression in A549 human epithelial cells 새창

  Abstract Background: Vitex rotundifolia has long been used in traditional medicine to treat asthma and other allergic diseases. Objective: To evaluate the anti-inflammatory mechanisms of V rotundifolia in cultured A549 human alveolar epithelial cells. Methods: In the present study, A549 cells were …

  최고관리자 2014-12-16 19:08:56
• Global gene analysis of erigeron canadensis-treated TNF-α-, IL-4- and IL-1β-stimulated A549 human epithelial cells 새창

  Abstract Background/Aims: This study was conducted to evaluate the anti-inflammatory mechanisms of Erigeron canadensis (EC) on the tumor necrosis factor-α (TNF-α)-, interleukin (IL)-4- and IL-1β-induced stimulation of A549 cells. Methods: In the present study, the anti-inflammatory effects of EC on…

  최고관리자 2014-12-16 19:07:29
• A new compound, 1H,8H-Pyrano[3,4-c]pyran-1,8-dione, suppresses airway epithelial cell inflammatory responses in a murine model of asthma 새창

  Abstract Clinical and experimental studies have established eosinophilia as a sign of allergic disorders. Activation of eosinophils in the airways is believed to cause epithelial tissue injury, contraction of airway smooth muscle and increased bronchial responsiveness. As part of the search for new…

  최고관리자 2014-12-16 19:01:29
• Microarray analysis of gene expression profiles in response to treatment with bee venom in lipopolysaccharide activated RAW 264.7 cells 새창

  Abstract Aim of the study: The therapeutic application of bee venom (BV) has been used in traditional medicine to treat diseases such as arthritis, rheumatism and pain. Macrophages produce molecules that are known to play roles in inflammatory responses. Material and methods: We performed microarra…

  최고관리자 2014-12-16 18:36:42
• Inhibition effects of Moutan Cortex Radicis on secretion of eotaxin in A549 human epithelial cells and eosinophil migration 새창

  Abstract Eosinophils have been implicated in a broad range of diseases, most notably allergic conditions (e.g. asthma, rhinitis and atopic dermatitis) and inflammatory diseases. These diseases are characterized by an accumulation of eosinophils in the tissue. Defining the mechanisms that control eo…

  최고관리자 2014-12-16 17:28:51
• Effects of bee venom on the pro-inflammatory responses in RAW264.7 macrophage cell line 새창

  Abstract The purpose of this study is to elucidate the molecular mechanism of anti-inflammatory effect of bee venom (BV), which has been used for the treatment of various inflammatory diseases in oriental medicine. With this aim, we examined the effects of BV on the nitric oxide (NO) production by …

  최고관리자 2014-12-16 15:17:51
• Ginsenoside Rg1 enhances CD4+ T-cell activities and modulates Th1/Th2 differentiation 새창

  Abstract Panax ginseng is commonly used as a tonic medicine in Asian countries such as Korea, China, and Japan. It has been reported that ginsenoside Rg1 in P. ginseng increases the proportion of T helper (Th) cells among the total number of T cells and promotes IL-2 gene expression in murine splen…

  최고관리자 2014-12-16 14:07:11

뉴스 게시판 내 결과

• CTLA-4 항체의 항암 효과를 높이는 새로운 혼합치료 새창

  단일항체를 통한 CTLA-4 (Cytotoxic T lymphocyte antigen-4)의 차단은 몇몇 암 환자들 중 2배 정도의 반응을 유도했고 말기 흑색종 치료를 위한 표준 치료법으로 미국 신약청 (FDA)의 허가를 받았다. 최근 미국 엠디 엔더슨 암 센터 (MD Anderson Cancer Center)의 제임스 엘리슨(James P. Allison) 교수 연구팀은 CTLA-4 차단제의 항종양 효과에서 ICOS(inducible co-stimulator)를 핵심적인 단백질로 동정했다 (Journal of Experimenta…

  최고관리자 2014-04-22 11:19:40
• 혼합된 항-CD40과 항-IL-23 단일 항체 치료의 항암 효과 새창

  종양이 유도하는 면역 억제는 잠재적으로 효과적인 암 치료법과 백신에 대한 주요한 장애들 중 하나로 남아 있다. 숙주 IL-23 는 종양 개시, 성장과 전이 과정에서 면역 반응을 억제하고 IL-23 의 중화는 IL-12 에 의존적인 항-종양 효과를 유도한다. 호주 퀸즈랜드 의대 (School of Medicine, University of Queensland)의 마이클 텡 (Michele W. L. Teng) 교수 연구팀은 IL-12 의 생산을 유도하는 자극적인 항-CD40 단일 항체와 IL-23의 종양 촉진 효과를 저해하는 항-IL…

  최고관리자 2014-03-03 13:04:09