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대표논문 게시판 내 결과
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Melittin derived peptide-drug conjugate, M-DM1, inhibits tumor progression and induces effector cell infiltration in melanoma by targeting M2 tumor-associated macrophages
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DOI doi.org/10.3389/fimmu.2023.1178776 JOURNAL Frontiers in Immunology TITLE Melittin derived peptide-drug conjugate, M-DM1, inhibits tumor progression and induces effector cell infiltration in mela…
최고관리자 2023-05-08 13:35:07 -
Neuroprotective effects of CD4+CD25+Foxp3+ regulatory T cells in a 3xTg-AD Alzheimer’s disease model
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DOI JOURNAL Oncotarget TITLE Neuroprotective effects of CD4+CD25+Foxp3+ regulatory T cells in a 3xTg-AD Alzheimer’s disease model
최고관리자 2016-10-05 14:51:39 -
Neuroprotective effects of bee venom phospholipase A2 in the 3xTg AD mouse model of Alzheimer’s disease
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DOI 10.1186/s12974-016-0476-z JOURNAL Journal of Neuroinflammation TITLE Neuroprotective effects of bee venom phospholipase A2 in the 3xTg AD mouse model of Alzheimer’s disease AbstractB…
최고관리자 2016-01-18 09:49:17 -
Neuro-protective effects of bee venom by suppression of neuroinflammatory responses in a mouse model of Parkinson's disease: Role of regulatory T cells
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Abstract In the present study, we sought to determine whether bee venom (BV) promotes the survival of dopaminergic (DA) neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson’s disease (PD). Treatment with BV prevented degeneration of DA neurons in the substanti…
최고관리자 2013-08-19 22:02:14 -
Molecular basis for interactions of G protein βΓ subunits with effectors
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ABSTRACT Both the α and βγ subunits of heterotrimeric guanine nucleotide–binding proteins (G proteins) communicate signals from receptors to effectors. Gβγ subunits can regulate a diverse array of effectors, including ion channels and enzymes. Gα subunits bound …
최고관리자 2013-08-20 00:48:00 -
Mapping of effector binding sites of transducin α-subunit using Gαt/Gαi1 chimeras
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TITLE Mapping of effector binding sites of transducin α-subunit using Gαt/Gαi1 chimeras JOURNAL Journal of Biological Chemistry Volume 271, Issue 1, 5 January 1996, Pages 413-424 PUBMED ID 10.1074/jbc.271.…
최고관리자 2013-08-20 00:58:15
기타논문 게시판 내 결과
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Enhanced Therapeutic Effect of Optimized Melittin-dKLA, a Peptide Agent Targeting M2-like Tumor-Associated Macrophages in Triple-Negative Breast Cancer
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DOI https://doi.org/10.3390/ijms232415751 JOURNAL International Journal of Molecular Sciences TITLE Enhanced Therapeutic Effect of Optimized Melittin-dKLA, a Peptide Agent Targeting M2-like Tumor-As…
최고관리자 2022-12-16 14:32:59 -
Therapeutic Effect of Melittin–dKLA Targeting Tumor-Associated Macrophages in Melanoma
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Abstract: Melanoma is an immunogenic tumor and a serious type of skin cancer. Tumor-associated macrophages (TAMs) express an M2-like phenotype and are involved in all stages of melanomagenesis; it is hence a promising target for cancer immunotherapy. We herein investigated whethe…
최고관리자 2022-03-15 10:14:59 -
Screening of phytochemicals effective on relieving cancer cachexia in cisplatin‑induced in vitro sarcopenia model
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Abstract Background Cancer cachexia is a lethal metabolic syndrome induced by cancer and chemotherapy administration and characterized by marked muscle wasting. Although hormone-related cancer therapies have been used for treatment of the cachexia, they have several side effects…
최고관리자 2022-03-08 15:21:37 -
Inhibitory effects of bee venom on mast cell-mediated allergic inflammatory responses
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Abstract Although bee venom (BV) is a toxin that causes bee stings to be painful, it has been widely used clinically for the treatment of certain immune‑associated diseases. BV has been used traditionally for the treatment of chronic inflammatory diseases. In this regard, the present study analyzed…
최고관리자 2019-07-26 15:25:28