경희대학교 한의과대학 배현수 교수 홈페이지

기타논문 게시판 내 결과

• Curcumin attenuates the scurfy-induced immune disorder, a model of IPEX syndrome, with inhibiting Th1/Th2/Th17 responses in mice 새창

  a b s t r a c t Background: Immunodysregulation polyendocrinopathy enteropathy X-linked syndrome (IPEX) is a lethal autoimmune disease caused by mutations in the Foxp3 gene scurfin (scurfy). Immunosuppressive therapy for IPEX patients has been generally ineffective and has caused severe side effect…

  최고관리자 2017-07-26 09:01:35
• Prophylactic effects of Lonicera japonica extract on dextran sulphate sodium-induced colitis in a mouse model by the inhibition of the Th1/Th17 response 새창

  Abstract Inflammatory bowel diseases (IBD) are chronically relapsing inflammatory disorders of the intestine. Although some therapeutic agents, including steroids, are available for the treatment of IBD, these agents have limited use. Therefore, dietary supplements have emerged as possible interven…

  최고관리자 2014-12-17 00:02:18
• Antiinflammatory effects of Epimedium brevicornum water extract on lipopolysaccharide-activated RAW264.7 macrophages 새창

  Abstract Epimedium brevicornum Maxim (Berberidaceae) possesses estrogenic properties. It is one of the most widespread herbal remedies used in Oriental medicine. The present study investigated the effects of Epimedium brevicornum water extract (EB) on proinflammatory mediators secreted from lipopol…

  최고관리자 2014-12-16 21:12:33
• Anti-inflammatory effects of Scutellaria baicalensis water extract on LPS-activated RAW 264.7 macrophages 새창

  Abstract Aim of the study: The root of Scutellaria baicalensis Georgi (Labiatae), also known as Scutellariae Radix, possesses anticancer, antiviral, and anti-inflammatory properties. And it is one of the most widespread herbal remedies used in Oriental medicine. In the present study, we investigate…

  최고관리자 2014-12-16 19:12:33
• The genome-wide expression profile of Scrophularia ningpoensis-treated thapsigargin-stimulated U-87MG cells 새창

  Abstract The endoplasmic reticulum (ER) is a principal site for protein synthesis, protein folding, calcium storage, and calcium signaling. Thapsigargin (TG), an inducer of ER stress, inhibits ER-associated Ca2+-ATPase and disrupts Ca2+ homeostasis. ER stress plays an important pathogenetic role in…

  최고관리자 2014-12-16 18:54:31
• Microarray analysis of gene expression profiles in response to treatment with bee venom in lipopolysaccharide activated RAW 264.7 cells 새창

  Abstract Aim of the study: The therapeutic application of bee venom (BV) has been used in traditional medicine to treat diseases such as arthritis, rheumatism and pain. Macrophages produce molecules that are known to play roles in inflammatory responses. Material and methods: We performed microarra…

  최고관리자 2014-12-16 18:36:42
• Inhibition of cell cycle progression via p27Kip1 upregulation and apoptosis induction by an ethanol extract of Rhus verniciflua Stokes in AGS gastric cancer cells 새창

  Abstract Botanical preparations are widely used by patient with cancer in Korea, Japan and China. Rhus verniciflua Stokes (RVS) has traditionally been used as a medicinal ingredient for the therapy of stomach and uterine cancer. In this study, we showed that exposure to an ethanol extract of RVS (5…

  최고관리자 2014-12-16 16:24:10
• Effects of bee venom on the pro-inflammatory responses in RAW264.7 macrophage cell line 새창

  Abstract The purpose of this study is to elucidate the molecular mechanism of anti-inflammatory effect of bee venom (BV), which has been used for the treatment of various inflammatory diseases in oriental medicine. With this aim, we examined the effects of BV on the nitric oxide (NO) production by …

  최고관리자 2014-12-16 15:17:51

뉴스 게시판 내 결과

• 항- GRP78 항체의 항암 효과 새창

  소포체(endoplasmic reticulum, ER)에서 쉐퍼론(chaperone)의 역할을 하는 GRP78은 종양 표면으로 이동하여 암의 성장과 전이 및 치료에 대한 저항성을 촉진시킨다. 세포 표면에서 GRP78의 암 형성 기능은 phosphoinositide 3-kinase (PI3K) 경로의 활성화에 대한 기여를 통해 이루어진다. 미국 남가주 대학 의대 (University of Southern California Keck School of Medicine)의 파카쉬 길 (Parkash S. Gill) 교수 연구팀은 새로운 …

  최고관리자 2013-10-07 16:48:37

배현수 교수 Story 게시판 내 결과

• 17년간의 치매치료제 개발역사 ~~ 앞으로 얼마나 더 해야 할까요??? 새창

  우리 실험실에서 가장 오랜 기간 동안 실험하고 있는 슬픈(?) 프로젝트 이야기를 할까 합니다. 시작은 1999년 10월로 기억되네요. 저는 미국에서 8년간의 유학생활을 마치고 1999년 9월 경희대학교에 부임하게 되었습니다. 말이 8년이지 미국에서 8년간 한의학은 잊어버리고 생명과학분야에만 묻혀 있다 보니 앞으로 한의과대학에서 어떤 연구를 해야 할 지 막막하기만 할 때이기도 합니다. 이때 한의대를 졸업하고 대학원에서 연구를 해보겠다며 생리학교실에서 실험준비를 하던 A(현 OO대교수)와 L(OO 한의원 원장)학생이 있었는데 이들…

  최고관리자 2016-10-05 14:47:26