Publications

대표논문

2000 ~ 2014

Research Article
Journal: Frontiers in Immunology / Doi:doi.org/10.3389/fimmu.2023.1178776
Date: 14 April 2023

Melittin derived peptide-drug conjugate, M-DM1, inhibits tumor progression and induces effector cell infiltration in melanoma by targeting M2 tumor-associated macrophages

Chanmi Jeong1†, Jeongdong Kim2,3†, Ik-Hwan Han1,4†, Soyoung Kim1, Ilseob Choi1, Hongsung Kim1,5, Jin-Hyun Jeong3* and Hyunsu Bae1,2*
» Download PDF (15.6M)
Research Article
Journal: Ivyspring International Publisher / Doi:10.7150/thno.75965
Date: 2022.11.07

Adoptive therapy with amyloid-β specific regulatory T cells alleviates Alzheimer’s disease

HyeJin Yang1†, Seon-Young Park1†, Hyunjung Baek1, Chanju Lee1,2, Geehoon Chung1, Xiao Liu3, Ji Hwan Lee1, Byungkyu Kim1, Minjin Kwon1, Hyojung Choi1, Hyung Joon Kim4, Jae Yoon Kim4, Younsub Kim5, Ye-Seul Lee5, Gaheon Lee6, Sun Kwang Kim1, Jin Su Kim7, You
» Download PDF (21.1M)
Research Article
Journal: Journal of Neuroinflammation / Doi:https://doi.org/10.1186/s12974-022-02512-z
Date: 11 June 2022

Neuroprotective efects of ex vivo-expanded regulatory T cells on trimethyltin-induced neurodegeneration in mice

Seon‑Young Park1 , HyeJin Yang1 , Minsook Ye2 , Xiao Liu3 , Insop Shim4 , Young‑Tae Chang3,5 and Hyunsu Bae1*
» Download PDF (4.6M)
Research Article
Journal: CANCER COMMUNICATIONS / Doi:10.1002/cac2.12276
Date: 9 February 2022

Combination of anti-PD-L1 antibody with peptide MEL-dKLA targeting M2 tumor-associated macrophages suppresses breast cancer metastasis

Chanju Lee1,3 Hyunji Lee1, Hayoon Cho1, Soyoung Kim2, Ilseob Choi2, Young-Sik Hwang4, Hyunju Jeong1, Hogi Jang1 Sehyun Pak1, Deok-Sang Hwang4, Ik-Hwan Han1, Hyunsu Bae1
» Download PDF (942.8K)
Research Article
Journal: frontiers in Immunology / Doi:https://doi.org/10.3389/fimmu.2020.00077
Date: 07 February 2020

Magnolol Attenuates Cisplatin-Induced Muscle Wasting by M2c Macrophage Activation

Chanju Lee, Hyunju Jeong, Hyunji Lee, Minwoo Hong, Seon-young Park and Hyunsu Bae*
» Download PDF (2.7M)
Research Article
Journal: Journal for ImmunoTherapy of Cancer / Doi:10.1186/s40425-019-0610-4
Date: 7 June 2019

Targeting of M2-like tumor-associated macrophages with a melittin-based pro-apoptotic peptide

Chanju Lee1 , Hyunju Jeong1 , Younghyeon Bae2 , Kyungmoon Shin2 , Sinwoo Kang2 , Hwikyung Kim2 , Jayoung Oh2 and Hyunsu Bae2*
» Download PDF (3.4M)
Research Article
Journal: Frontiers in Immunology / Doi:10.3389/fimmu.2019.00530
Date: 21 March 2019

Intratracheal Ovalbumin Administration Induces Colitis Through the IFN-γ Pathway in Mice

Kyoung-Hwa Jung1†, Dasom Shin1†, Sejun Kim1 , Daeun Min1 , Woogyeong Kim2 , Jinju Kim2 , Gihyun Lee3 * and Hyunsu Bae1 *
» Download PDF (2.4M)
Research Article
Journal: SCIENTIFIC REPORTS / Doi:https://doi.org/10.1038/s41598-018-35030-1
Date: 26 November 2018

Bee venom phospholipase A2 ameliorates Alzheimer’s disease pathology in Aβ vaccination treatment without inducing neuro-infammation in a 3xTg-AD mouse model

Hyunjung Baek1, Chan-ju Lee1, Da BinChoi1, Nam-sik Kim2, Yong-Suk Kim 2, Young JunYe3, Youn-Sub Kim3, Jin Su Kim4, Insop Shim5 & Hyunsu Bae
» Download PDF (3.5M)
Research Article
Journal: SCIENTIFIC REPORTS / Doi:https://doi.org/10.1038/s41598-018-35320-8 2
Date: 15 November 2018

A standardized herbal extract PM014 ameliorates pulmonary fbrosis by suppressing the TGF-β1 pathway

Kyung Hwa Kim1, Sujin Lee1, Hyunji Lee1, Dasom Shin1, Daeun Min1, Miran Kim2, Byeol Ryu3 , HyeonWoo Kim3 & Hyunsu Bae
» Download PDF (3.3M)
Research Article
Journal: Frontiers in Immunology / Doi:https://doi.org/10.3389/fimmu.2017.01344
Date: 31 October 2017

Cigarette Smoking Triggers Colitis by IFN-γ+ CD4+ T Cells

Gihyun Lee1†, Kyoung-Hwa Jung1†, Dasom Shin1, Chanju Lee1, Woogyeong Kim2, Sujin Lee1, Jinju Kim2*, Hyunsu Bae1*
» Download PDF (3.9M)
Research Article
Journal: Oncotarget / Doi:.
Date: June 27, 2017

Melittin suppresses tumor progression by regulating tumorassociated macrophages in a Lewis lung carcinoma mouse model

Chanju Lee1, Sung-joo S. Bae2, Hwansoo Joo1 and Hyunsu Bae1
» Download PDF (7.3M)
Research Article
Journal: SCIENTIFIC REPORTS / Doi:10.1038/srep45001
Date: 21 March 2017

Standardized Herbal Formula PM014 Inhibits Radiation-Induced Pulmonary Inflammation in Mice

Jee-Youn Kim1,*, Dasom Shin2,*, Gihyun Lee2, Jin-Mo Kim1, Dongwook Kim2, Yong-Min An1, Byung Rok Yoo1, Hanna Chang1, Miran Kim3, Jaeho Cho1 & Hyunsu Bae2
» Download PDF (1.6M)
Research Article
Journal: Oncotarget / Doi:.
Date: October 04, 2016

Neuroprotective effects of CD4+CD25+Foxp3+ regulatory T cells in a 3xTg-AD Alzheimer’s disease model

Hyunjung Baek1, Minsook Ye1, Geun-Hyung Kang1, Chanju Lee1, Gihyun Lee1, DaBin Choi1, Jaehoon Jung1, Hyunseong Kim2, Seonhwa Lee3, Jin Su Kim3, Hyun-ju Lee4, Insop Shim4, Jun-Ho Lee5 and Hyunsu Bae1
» Download PDF (2.1M)
Research Article
Journal: Experimetal & Molecular Medicine / Doi:10.1038/emm.2016.83
Date: 17 May 2016

Adenovirus-mediated Foxp3 expression in lung epithelial cells reduces airway inflammation in ovalbumin and cockroach-induced asthma model

Soojin Park1,4, Hwan-Suck Chung2,4, Dasom Shin1, Kyung-Hwa Jung1, Hyunil Lee1, Junghee Moon3 and Hyunsu Bae1
» Download PDF (3.0M)
Research Article
Journal: Experimental & Molecular Medicine / Doi:10.1038/emm.2016.49
Date: 8 July 2016

Bee venom phospholipase A2 ameliorates motor dysfunction and modulates microglia activation in Parkinson’s disease alpha-synuclein transgenic mice

Minsook Ye1, Hwan-Suck Chung2, Chanju Lee1, Joo Hyun Song1, Insop Shim3, Youn-Sub Kim4 and Hyunsu Bae1
» Download PDF (2.5M)

경희대학교 한의과대학 배현수 교수 연구실

Prof. Hyunsu Bae / College of Korean Medicine, Kyung Hee Univeristy, Seoul, Korea

2018 | Bee venom phospholipase A2 ameliorates Alzheimer’s disease pathology in Aβ vaccination treatment without inducing neuro-infammation in a 3xTg-AD mouse model…

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대표논문

DOI	https://doi.org/10.1038/s41598-018-35030-1
JOURNAL	SCIENTIFIC REPORTS
TITLE	Bee venom phospholipase A2 ameliorates Alzheimer’s disease pathology in Aβ vaccination treatment without inducing neuro-infammation in a 3xTg-AD mouse model