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경희대학교 한의과대학 배현수 교수 연구실
Prof. Hyunsu Bae / College of Korean Medicine, Kyung Hee Univeristy, Seoul, Korea
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Research Article
Journal:
Frontiers in Immunology
/ Doi:doi.org/10.3389/fimmu.2023.1178776
Date: 14 April 2023
Melittin derived peptide-drug conjugate, M-DM1, inhibits tumor progression and induces effector cell infiltration in melanoma by targeting M
2
tumor-associated macrophages
Chanmi Jeong1†, Jeongdong Kim2,3†, Ik-Hwan Han1,4†, Soyoung Kim1, Ilseob Choi1, Hongsung Kim1,5, Jin-Hyun Jeong3* and Hyunsu Bae1,2*
» Download PDF
(15.6M)
Research Article
Journal:
CANCER COMMUNICATIONS
/ Doi:10.1002/cac2.12276
Date: 9 February 2022
Combination of anti-PD-L1 antibody with peptide MEL-dKLA targeting M
2
tumor-associated macrophages suppresses breast cancer metastasis
Chanju Lee1,3 Hyunji Lee1, Hayoon Cho1, Soyoung Kim2, Ilseob Choi2, Young-Sik Hwang4, Hyunju Jeong1, Hogi Jang1 Sehyun Pak1, Deok-Sang Hwang4, Ik-Hwan Han1, Hyunsu Bae1
» Download PDF
(942.8K)
Research Article
Journal:
frontiers in Immunology
/ Doi:https://doi.org/10.3389/fimmu.2020.00077
Date: 07 February 2020
Magnolol Attenuates Cisplatin-Induced Muscle Wasting by M
2
c Macrophage Activation
Chanju Lee, Hyunju Jeong, Hyunji Lee, Minwoo Hong, Seon-young Park and Hyunsu Bae*
» Download PDF
(2.7M)
Research Article
Journal:
Journal for ImmunoTherapy of Cancer
/ Doi:10.1186/s40425-019-0610-4
Date: 7 June 2019
Targeting of M
2
-like tumor-associated macrophages with a melittin-based pro-apoptotic peptide
Chanju Lee1 , Hyunju Jeong1 , Younghyeon Bae2 , Kyungmoon Shin2 , Sinwoo Kang2 , Hwikyung Kim2 , Jayoung Oh2 and Hyunsu Bae2*
» Download PDF
(3.4M)
Research Article
Journal:
SCIENTIFIC REPORTS
/ Doi:https://doi.org/10.1038/s41598-018-35030-1
Date: 26 November 2018
Bee venom phospholipase A
2
ameliorates Alzheimer’s disease pathology in Aβ vaccination treatment without inducing neuro-infammation in a 3xTg-AD mouse model
Hyunjung Baek1, Chan-ju Lee1, Da BinChoi1, Nam-sik Kim2, Yong-Suk Kim 2, Young JunYe3, Youn-Sub Kim3, Jin Su Kim4, Insop Shim5 & Hyunsu Bae
» Download PDF
(3.5M)
Research Article
Journal:
Oncotarget
/ Doi:.
Date: October 04, 2016
Neuroprotective effects of CD4+CD
2
5+Foxp3+ regulatory T cells in a 3xTg-AD Alzheimer’s disease model
Hyunjung Baek1, Minsook Ye1, Geun-Hyung Kang1, Chanju Lee1, Gihyun Lee1, DaBin Choi1, Jaehoon Jung1, Hyunseong Kim2, Seonhwa Lee3, Jin Su Kim3, Hyun-ju Lee4, Insop Shim4, Jun-Ho Lee5 and Hyunsu Bae1
» Download PDF
(2.1M)
Research Article
Journal:
Experimental & Molecular Medicine
/ Doi:10.1038/emm.2016.49
Date: 8 July 2016
Bee venom phospholipase A
2
ameliorates motor dysfunction and modulates microglia activation in Parkinson’s disease alpha-synuclein transgenic mice
Minsook Ye1, Hwan-Suck Chung2, Chanju Lee1, Joo Hyun Song1, Insop Shim3, Youn-Sub Kim4 and Hyunsu Bae1
» Download PDF
(2.5M)
Research Article
Journal:
Journal of Neuroinflammation
/ Doi:10.1186/s12974-016-0476-z
Date: 2016
Neuroprotective effects of bee venom phospholipase A
2
in the 3xTg AD mouse model of Alzheimer’s disease
Minsook Ye1, Hwan-Suck Chung2, Chanju Lee1, Moon Sik Yoon1, A. Ram Yu3, Jin Su Kim3, Deok-Sang Hwang4, Insop Shim5 and Hyunsu Bae1*
» Download PDF
(2.0M)
Research Article
Journal:
Molecular Neurobiology
/ Doi:10.1007/s12035-015-9458
Date: 07 October 2015
Standardized Herbal Formula PM01
2
Decreases Cognitive Impairment and Promotes Neurogenesis in the 3xTg AD Mouse Model of Alzheimer’s Disease
Minsook Ye, Hwan-Suck Chung, Yong Ho An, Su-jin Lim, Won Choi, A. Ram Yu, Jin Su Kim, Manho Kang, Seunghun Cho, Insop Shim, Hyunsu Bae
Research Article
Journal:
The Journal of Immunology
/ Doi:10.4049/jimmunol.1500386
Date: September 11, 2015
Bee Venom Phospholipase A
2
, a Novel Foxp3+ Regulatory T Cell Inducer, Protects Dopaminergic Neurons by Modulating Neuroinflammatory Responses in a Mouse Model of Parkinson’s Disease
Eun Sook Chung,*,1 Gihyun Lee,*,1 Chanju Lee,* Minsook Ye,* Hwan-suck Chung,* Hyunseong Kim,* Sung-joo S. Bae,† Deok-Sang Hwang,‡ and Hyunsu Bae*
Research Article
Journal:
Kidney International
/ Doi:10.1038/ki.2015.147
Date: 20 May 2015
Phospholipase A
2
inhibits cisplatin-induced acute kidney injury by modulating regulatory T cells by the CD
2
06 mannose receptor
Hyunseong Kim1, Hyojung Lee1, Gihyun Lee1, Hyunil Jang1, Sung-Su Kim2, Heera Yoon1,Geun-Hyung Kang1, Deok-Sang Hwang3, Sun Kwang Kim1, Hwan-Suck Chung4 and Hyunsu Bae1
Research Article
Journal:
Journal of Immunology
/ Doi:10.4049/jimmunol.1001373
Date: September 21, 2010.
Methyl gallate exhibits potent antitumor activities by inhibiting tumor infiltration of CD4+CD
2
5+ regulatory T cells
Heekyung Lee*, Hyojung Lee*, Youngjoo Kwon*, Jun-Ho Lee*, Jinju Kim†, Min-Kyu Shin*, Sung-Hoon Kim‡ and Hyunsu Bae*
Research Article
Journal:
Kidney International (2010) 78, 1100–1109
/ Doi:10.1038/ki.2010.139
Date: 12 May 2010
CD4+ CD
2
5+ regulatory T cells attenuate cisplatin-induced nephrotoxicity in mice
Hyojung Lee1, Dukhee Nho1, Hwan-Suck Chung1, Heekyung Lee1, Min-Kyu Shin1, Sung-Hoon Kim2 and Hyunsu Bae1
Research Article
Journal:
Journal of Experimental Medicine Volume 191, Issue 1, 3 January 2000, Pages 9-21
/ Doi:10.1084/jem.191.1.9
Date: 19 October 1999
The nuclear factor of activated T cells (NFAT) transcription factor NFATp (NFATc
2
) is a repressor of chondrogenesis
Ann M. Rangera, Louis C. Gerstenfeldd, Jinxi Wangb, Tamiyo Kond,e, Hyunsu Baea, Ellen M. Gravallesec, Melvin J. Glimcherb and Laurie H. Glimchera,c